Philadelphia Phillies at Houston Astros odds, picks and predictions

Skyler Carlin
Sportsbook Wire

The Philadelphia Phillies (87-74) will face the Houston Astros (105-56) to close out both teams' regular-season schedules Wednesday. First pitch from Minute Maid Park is at 4:10 p.m. ET. Let's analyze Tipico Sportsbook's lines around the Phillies vs. Astrosodds with MLB picks and predictions.

Season series: tied 1-1

The Phillies were defeated by the Astros 10-0 Tuesday as LHP Ranger Suarez allowed 6 ER in only 3 IP. Philadelphia has the No. 3 wild-card spot in the NL despite the lopsided loss, ending a 10-year drought of not making the playoffs.

The Astros got a stellar performance from RHP Justin Verlander in his final start of the season Tuesday as he pitched 5-scoreless innings with 10 K. Houston owns the No. 1 seed in the AL, so they have a 1st-round bye in the postseason.

Play our free daily Pick'em Challenge and win! Play now !

Phillies at Astros projected starters

LHP Bailey Falter vs. LHP Framber Valdez

Falter (6-4, 3.90 ERA) makes his 16th start and 20th appearance. He has a 1.21 WHIP, 1.8 BB/9 and 8.0 K/9 through 83 IP.

  • Has been credited with a win in 6 of his last 8 starts
  • Has allowed 2 or fewer ER in 6 of his last 8 outings

Valdez (16-6, 2.89 ERA) makes his 31st start. He has a 1.17 WHIP, 3.0 BB/9 and 8.4 K/9 through 196 1/3 IP.

  • Has given up 10 combined ER in his last 2 starts
  • Had 25 straight starts of 6 IP or more before his last 2 contests

Phillies at Astros odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 9:43 a.m. ET.

  • Moneyline (ML) : Phillies +150 (bet $100 to win $150) | Astros -190 (bet $190 to win $100)
  • Run line (RL)/Against the spread (ATS) : Phillies +1.5 (-140) | Astros -1.5 (+112)
  • Over/Under (O/U) : 7.5 (O: -103 | U: -117)

Claim your risk-free bet up to $350. Catch the excitement and start betting with Tipico Sportsbook! New customer offer in CO and NJ. 21+, see Tipico.com for Terms and Conditions. Bet now!

Phillies at Astros picks and predictions

Prediction

Astros 5, Phillies 3

Moneyline

I'm going to PASS on the moneyline in this game as I see the Astros closing the season out with a win, but the line is a little too steep to wager.

Even if Houston sits some of its starters, the lineup is deep enough to beat Philadelphia at home.

Run line/Against the spread

After seeing the Astros put up 10 runs Tuesday, it's clear that they want to make sure their bats are ready for the playoffs as they'll have a 1st-round bye.

With that in mind, give me ASTROS -1.5 (+112) at home in the final game of the regular season.

If you aren't comfortable taking Houston by multiple runs, ASTROS -0.5 FIRST 5 INNINGS (-125) is a solid alternative.

Over/Under

OVER 7.5 (-103) is where I'm going in this game as the bats of the Astros are hot right now and Valdez has been shaky in recent starts. The Over has hit in 3 of his last 4 starts.

The Over has also hit in 5 of the last 7 meetings between the Phillies and the Astros.

Want action on this game or any other MLB contests? Bet legally online with a trusted partner: Tipico Sportsbook, SportsbookWire's official sportsbook partner in CO and NJ. Bet now!

If you're looking for more sports betting picks and tips, access all of our content at SportsbookWire.com and BetFTW, or try out our USA TODAY Parlay Calculator. Please gamble responsibly.

Follow Skyler Carlin on Twitter. Follow SportsbookWire on Twitter and like us on Facebook.

Additional MLB coverage:

BaseballHQ Fantasy Baseball

BaseballPress.com: Your source for every MLB lineup