Castillo died at in 2002 from cancer at age 51 after years playing with Ozzy Osbourne, Motley Crue and other acts.
He graduated in 1968 with the first class to attend the school and launched his career playing with local bands.
His sister began pushing for the honor two years ago and the renaming was approved by the Albuquerque Public Schools board last summer. The official renaming ceremony is set for Tuesday.
"This speaks to his legacy," Christine Castillo told tells the Albuquerque Journal ( http://bit.ly/TSicX1). "This speaks to how well he did in music and how well people thought of him."
His mother, Margaret Castillo, said the honor is somewhat bittersweet.
"I'm having mixed feelings," she said. "It's sad that he's not here to enjoy his achievement. So it's a sad occasion and a happy occasion."
Randy Castillo began playing drums in elementary school, then switched to the trumpet, Christine Castillo said. But he tired of the brass and wanted to go back to the drums.
A biography posted on West Mesa's website says he was a drummer in the school's Mustang marching band, wrote the drum cadence it still uses and was named to the all-state symphonic band.
He began his meteoric professional rise after he joined his first
In the early '70s, he moved to Los Angeles and played for groups such as The Mudd before he joined Lita Ford in 1984 for her album, "Dancin' on the Edge," Christine Castillo said.
Not long after, Motley Crue drummer Tommy Lee introduced Randy Castillo to Ozzy Osbourne, who invited Randy to play during the band's "Live and Loud Tour" in 1993.
Castillo played with Osbourne for 10 years and later played for Motley Crue.
Margaret Castillo remembered that just before getting the audition for Ozzy Osbourne, Randy Castillo had broken his leg in a skiing accident.
"He cut the cast off himself and flew to England to audition," she said. "And he got the job."
Information from: Albuquerque Journal, http://www.abqjournal.com